Selection of publications

  1. Rost S, Fregin A, Ivaskevicius V, Conzelmann E, Hörtnagel K, Pelz H-J, Lappegard K, Seifried E, Scharrer I, Tuddenham EGD, Müller CR, Strom TM, Oldenburg J (2004) Mutations in the VKORC1 gene cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 427:537-41. (with Editorial from E. Sadler)
  2. Rost S, Fregin A, Koch D, Compes M, Müller CR, Oldenburg J (2004) Compound heterozygous mutations in the Gamma-Glutamyl-Carboxylase gene cause combined deficiency of all vitamin K-dependent blood coagulation factors. Brit J Haematol 126:546-549
  3. Watzka M, Geisen C, Seifried E, Oldenburg J (2004) Sequence of the rat factor VIII cDNA. Thromb Haemost 91:38-42
  4. Oldenburg J, Schröder J, Brackmann HH, Müller CR, Schwaab R, Tuddenham E (2004) Environmental and genetic factors influencing inhibitor development. Semin Hematol 41 (Suppl 1):82-88
  5. Fregin A, Rost S, Wolz W, Krebsova A, Mueller CR, Oldenburg J (2002) Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors (FMFD) to the centromeric region of chromosome 16. Blood 100:3329-3332
  6. Leuer M*, Oldenburg J*, Lavergne JM, Ludwig M, Fregin A, Eigel A, Ljung R, Goodeve A, Peake I, Olek K (2001) Somatic mosaicism in hemophilia A: A fairly common event. Am J Hum Genet 69:75-87 (*contributed equally)
  7. Oldenburg J, Kriz K, Wuillemin WA, Maly FE, Felten von A, Siegemund A, Keeling DM, Baker P, Chu K, Konkle B, Lämmle B, Albert T (2001) Genetic predisposition to bleeding during oral anticoagulant therapy: Evidence for common founder mutations (FIXVal-10 and FIXThr-10) and an independent CpG hotspot mutation (FIXThr-10). Thromb Haemost 85:454-457
  8. Oldenburg J, Schwaab R (2001) Molecular biology of coagulation factors. Semin Thromb Hemost 27:313-324
  9. Oldenburg J, Brederlow von B, Fregin A, Rost S, Wolz W, Eberl W,Eber S, Lenz E, Schwaab R, Brackmann HH, Effenberger W, Harbrecht U, Schurgers L, Vermeer C, Müller CR (2000) Congenital deficiency of vitamin K dependent coagulation factors in two families presents as a defect of the vitamin K-epoxide-reductase-complex. Thromb Haemost 84:937-941
  10. Oldenburg J, Rost S, El-Maarri O, Leuer M, Olek K, Müller CR, Schwaab R (2000) De novo factor VIII intron 22 inversion in a female carrier presents as a somatic mosaicism. Blood 96:2905-2906

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