Molecular Haemostasis

The parts of our group providing diagnostic services are working at the Universities of Frankfurt and Wuerzburg in close cooperation with Prof. Müller-Reible (Division of Molecular Genetics, Biocenter Würzburg). We have established an overregional center with highly efficient mutation screening protocols for a broad range of blood coagulation genes and related phenotypes.The most significant mutation databases comprise 1850 patients with haemophilia A, 40 patients with faxtor XIII deficiency and 13 different mutations within the newly identified Vitamin K epoxide reductase (VKORC1) gene.