Molecular Haemostasis : Directory of Services

Directory of Services

Genetic analyses of coagulation disorders

Procoagulatory Factors

• Fibrinogen, FGA, FGB, FGG (Afibrinogenaemia, Dysfibrinogenaemia, Hypofibrinogenaemia)
• Factor II, F2
• Factor V, F5
• Factor VII, F7
• Factor VIII, F8 (Haemophilia A)
• Factor IX, F9 (Haemophilia B)
• Factor X, F10
• Factor XI, F11
• Factor XII, F12
• Factor XIII, F13A, F13B

Inhibitory Factors

• Protein C, PROC
• Protein S, PROS
• Antithrombin, SERPINC1

Pharmacogenetic

• Vitamin-K-Epoxid-Reductase, VKORC1 (Coumarin resistance, -sensitivity, hereditary deficiency of factors II, VII, IX, X, PS, PC, [VKCFD2])
• Cytochrome P450 2C9, CYP2C9 (Coumarin resistance, -sensitivity)
• Cyclooxygenase, PTGS1 (ASS resistance)

Other Genes

• Kininogen, KNG
• Prekallikrein, KLKB1
• Carboxylase, GGCX (hereditary deficiency of factors II, VII, IX, X, PS, PC, [VKCFD1])
• LMAN1 (combined FV-FVIII-deficiency)
• MCFD2 (combined FV-FVIII-deficiency)